Ciproxin 500 mg per bronchite ous nodule), and oral corticosteroids (hydrocortisone 1,000 mg daily for 3 to 4 months and then every 6 thereafter). This treatment regimen has also been suggested in other clinical trials.18-20
The use of intravenous calcium does not seem to reduce the rate of decline; however, it may delay the appearance of secondary pulmonary complications that were initially seen by intravenous calcium treatment. In contrast, high-dose corticosteroids significantly reduce secondary pulmonary complications with or without a reduction in the rate of decline.22,23
A randomized double-blind, placebo-controlled trial was conducted evaluating the use of intravenous calcium (400 mg daily for 3 months) versus topical corticosteroids (30 mg twice daily) in a cohort of patients with chronic bronchitis and at least 2 years of asthma duration. Although the results of trial suggested that intravenous calcium led to more pronounced improvement than corticosteroids in terms of both objective disease activity and subjective well-being, the difference between groups was not significant (mean difference, 4.6 months).24 In general, the use of calcium does not lead to an improvement in disease activity despite corticosteroid treatment because the dose of calcium can be increased to achieve optimal improvement but the effects on disease activity are only minimal.24,25
Cranial Phototherapeutic Therapy or Laser for Acute Asthma
In a prospective 12-week, placebo-controlled study, we randomly assigned 24 adults with acute asthma or chronic bronchitis to receive 4 sessions of irradiation with a laser and course of topical therapy, or placebo. Although the clinical benefit was modest, it not statistically significant.26,27
Cranial Phototherapeutic Therapy
In a randomized double-blind, sham-controlled study, we randomly assigned 16 adult patients with acute asthma to receive 4 sessions of irradiation with a laser and course of topical therapy, or placebo, with a total of 60 min each session. Although the clinical benefit was modest and did not reach statistical significance, it was not statistically significant.28 A randomized double-blind, placebo-controlled pilot study showed an improvement in the mean pulmonary function test when 12 patients received cranial laser therapy (3 sessions of and 4 placebo) versus 13 patients who received placebo therapy.29 Cranial phototherapeutic therapy is generally associated with an increased efficacy of bronchodilators and may offer the therapeutic potential to treat chronic bronchitis in persons with asthma.30
Cranial Laser Therapy
Cranial laser therapy using a apparatus in the office has been used successfully for the first time in adults with chronic bronchitis as a single-session treatment to relieve cough.31,32 The single treatment is effective in improving patient-reported symptoms and overall xanax type over the counter health outcomes.33,34 Cranial laser therapy was also shown to reduce the duration of acute episodes with asthma.33
In a prospective randomized, placebo-controlled study, patients were randomly assigned either to receive 4 short (15-min) sessions of cranial laser treatment with a light level of 5 to 10 cm and an intensity of 50 or 60 J/cm2 placebo. Cranial laser treatment led to an average Brand xanax 2mg decrease of the number exacerbations over a 2-year period; however, the effect of treatment was not statistically significant. However, the treatment with laser had a significant beneficial role in lowering the time of each exacerbation period.34 In a prospective randomized, sham-controlled study, the same patients as described below participated in three 12-week clinical trials. the second trial, one-half of cranial laser group received a single-session session that had light level of 5 to over the counter medication like xanax 10 cm, with an intensity of 45 J/cm2 (equivalent to 5 15 cm of light, which corresponds to a 5/500 lux wavelength range). This treatment led to an increase in the incidence of exacerbation.25 third clinical trial a single session of laser, the second clinical trial included 16 patients randomly assigned to receive cranial laser therapy with a light level of 10 to 11 cm, 6.5 8 J/cm2 (equivalent to pharmacy online australia 10 12 cm of light, which corresponds to a 5° 10° wavelength range). Cranial laser treatment led to an increase in the intensity of light and increased the frequency (the total time of treatment with irradiated light was decreased) of acute exacerbations by approximately 33%.34 Cranial laser therapy is a feasible option for exacerbation management in adults with acute or chronic bronchitis.
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